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B2 Cell Division

B2.1 Cell Division

Question Answer
Why does an organism need new cells? to grow and to replace worn out or damaged cells
What is a gene? a gene is a section of the chromosome that controls a characteristic or part of a characteristic
What is a gene made of? a gene is made of the chemical DNA
What is DNA? it is a special chemical used to build chromosomes and genes
Where are the chromosomes? in the nucleus of the cell
What is a chromosome? a chromosome is a set of genes connected together that carry genetic information and is made of DNA
What determines a characteristic of an organism? some characteristics are the result of a single gene but most characteristics are the result of many different genes working together
What is the relationship between chromosomes and genes? genes are grouped together to form chromosomes with a single chromosome often carrying several hundred or even thousands of genes
How many chromosomes are in the human cell? 46 organised into 23 pairs
Where does each member of a chromosome pair come from? 1 chromosome from each parent
Name the two human gametes? sperm and ovum cells
How many chromosomes in a human gamete? 23 single chromosomes
What is the cell cycle? cells grow and divide in a series of stages called the cell cycle
What is the process of cell division called? mitosis
What does mitosis produce? two genetically identical cells called the daughter cells
Why do organisms need to do mitosis? to produce new cells for growth or to replace worn out or damaged cells
How many parents are there in asexual reproduction? just one
How many parents are there in sexual reproduction? two
How does asexual reproduction happen? offspring are produced by mitosis by a single parent
Why are offspring genetically identical to the parent in asexual reproduction? because the offspring are produced by mitosis and mitosis produces genetically identically cells
How long does it take for the cell cycle to complete? it varies taking anywhere from 24 hours to several years depending on the type of cell
How many stages are there in the cell cycle? three
Describe the first stage of the cell cycle • the longest stage
• cells grow bigger and increase their mass
• they replicate their DNA to create copies of all chromosomes
• they increase the number of organelles like mitochondria and chloroplasts
Describe the second stage of the cell cycle • mitosis starts
• one set of chromosomes is to pulled to each side of the cell
• the cell is dividing
Describe the third and final stage of the cell cycle • the cytoplasm divides
• the cell membranes divides
• two daughter cells are formed
What is formed when a cell undergoes mitosis? two genetically identical daughter cells
Compare cell division in a child and an adult • in a child, cell division produces new cells faster than the old ones die
• in an adult, cell division produces new cells at roughtly the samre rate as the old ones die
What is the average number of cell deaths per minute in humans? about 300 million body cells die every minute

B2 Cell Division

B2.2 Growth and Differentiation

Question Answer
How many cells are there in the human body? Estimates range from 15 to 100 trillion
Why are the cells of a multicellular organism different? as cells divide and grow, they differentiate
What are the undifferentiated cells of the early embryo called? stem cells
How does a stem cell differentiate? some genes are turned off and are switched on
Name some differentiated cells in humans. nerve, skin, or muscle cells
When muscle cells divide by mitosis, what type of cells do they produce? once a cell differentiates, it can only produce cells of the same kind by mitosis, so muscle cells
Can all differentiated cells divide by mitosis? no - most can but not all
Name two differentiated cells that cannot divide by mitosis? red blood cells and skin cells
How do red blood cells and skin cells reproduce to produce new cells for growth and repair? adult stem cells produce new blood cells and skin cells
How do nerve cells divide to produce new nerve cells? nerve cells do not divide once they are differentiated and there are no adult stem cells to produce new nerve cells so when nerve cells are damaged they are not replaced
Can differentiated animal cells redifferentiate? no, once a muscle cell, always a muscle cell
Can adult plant cells redifferentiate? unlike animal cells, most plant cells can differentiate all their lives - differentiation in plants cells is not permanent
Where are undifferentiated cells in plants? they are generated at active regions in the roots and the stems called meristems
What happens in the meristems? mitosis takes place continuously
How long do plants grow for? all their lives
What is producing identical offspring called? cloning
Can new plants be produced from a leaf? yes, under the right conditions a plant cell will become undifferentiated so a leaf can be split into small sections each of which will form a new tiny plant that is gentically identical
Which are easy to clone, plants or animals? plants are easy to clone while animals are very difficult to clone.

B2 Cell Division

B2.3 Stem Cells

Question Answer
What happens when an egg meets a sperm? they fuse to form a single cell called a zygote
What happens to the zygote? it divides by mitosis until it forms a hollow ball of cells called an embryo
What are the inner cells of the embryo called? embryonic stem cells
What happens to embryonic stem cells? they differentiate to form specialised cells
What is an adult stem cell? adults have a small number of stem cells known as adult stem cells
Can an adult stem cell differentiate? yes, it can differentiate to form specialised cells
Where in humans can adult stem cells be found? bone marrow is a good scource of stem cells in humans
Why can spinal injuries cause paralysis? because nerve cells cannot repair or replace themselves
What is the cause of type 1 diabetes? specialised cells in the pancreas that are supposed to produce insulin are not working
How is it hoped that stem cells can help spinal injuries? it is hoped that stem cells will differentiate and replace the damaged nerve cells
How is it hoped that stem cells can cure type 1 diabetes? it is hoped that the stem cells will differentiate into working cells that produce insulin to replace the damaged cells in the pancreas
Name 3 conditions that may benefit from stem cells other than paralyis and diabetes? dementia, infertility, and new organs for transplant
How are plants best cloned? by taking cells from the meristems large numbers of plants can be made quickly and economically
Name industries that use plant cloning? horticulture, agriculture, and research
How could cloning be used to combat plant extinction? cloning can be used to produce very large numbers of rare plants
What is the value of cloning plants to research? it produces large numbers of identical cells for scientist to test with
How does plant cloning assist agriculture? large numbers of plants with special features like fruit colour and shape or disease resistance can be produced as in the banana trade
How has plant cloning affected horticulture? orchids are hard to grow, grow very slowly, and used to be rare but are now available cheaply in large numbers because plant cloning can produce large large numbers of plants cheaply and quickly

B2 Cell Division

B2.4 Stem Cell Dilemmas

Question Answer
Where do large numbers of stem cells come from? aborted embryos and spare embryos from fertility treatment
What are the issues with stem cell research? • ethical and religious views about embryos
• the slow pace of progress with research
• the possiblity that stem cells may cause cancer
• the concern that adult stem cells may be infected with viruses
• the view that there are more important areas of medical research
What are the objections to sourcing stem cells from embryos? • some people are uncomfortable with making use of a potential human beings
• some people do not like the fact that the embryo cannot give permission to be used
• some people's religious beliefs prohibit abortion and the use of embryos
What has progress been like in stem cell research? relatively slow, difficult, expensive and hard to control over 20 years of research, in paticular, the signals that control differentiation are not yet understood
Why is there a concern that stem cells may cause cancer? because this has been observed in the treatment of mice and some autoimmune diseases in humans
What are the concerns about using adult stem cells? • they may be infected by viruses
• they may trigger an immune response and be rejected
Where can embryonic stem cells be found other than in embryos? in the blood of the umbilical cord and the amniotic fluid
What is the benefit of using embryonic stem cells from the blood of the umbilical cord? it overcomes the ethical and religious objections to using embryos for stem cells
What is the benefit of using adult stem cells? it overcomes the ethical and religious objections to using embryos for stem cells
What is therapeutic cloning? it involves using cells from an adult to produce a cloned embryo
What is the benefit of therapeutic cloning? the stem cells are genetically identical to the recipient so any new organs produced should not be rejected by the patient
What potential therapies are being considered with stem cell research? • spinal cord injuries
• diabetes
• heart damage due to heart attack
• eyesight for blind people
• damaged bone and cartilage

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